According to MMA Weekly, the UFC 122 main event has been changed as Vitor Belfort has been forced out due to an undisclosed injury. Replacing him is Nate Marquardt who is fresh off his UFN 22 victory over Rousimar Palhares:

An injury has forced Vitor Belfort out of his UFC 122 main event fight against Yushin Okami in Germany. In to replace Belfort will be Nate Marquardt, who just picked up a TKO win over Rousimar Palhares at UFC Fight Night 22.

Marquardt's placement in the fight was confirmed to MMAWeekly.com by sources close to the bout, who stated the fight has been signed for the new main event at UFC 122.

UFC 122 was just officially announced yesterday, and they were marketing it with the winner of that bout getting the next title shot. With Belfort being injured, and Sonnen's shot being in jeopardy for the failed drug test, one has to wonder if they would still decide to give the winner of this bout that title shot -- and if they do, will people still be interested in watching that?