MMA Weekly reports:

Strikeforce vice president Mike Afromowitz, during an appearance on MMAWeekly Radio on Wednesday, said the promotion expects the champ back after he finishes the films, while maintaining their support for Le’s desire to pursue a second career in acting.

...

“You know, it’s a possibility he might wind up fighting (Kazuo) Misaki, who we were hoping he’d fight last November, but there was scheduling conflicts on Misaki’s side, so it didn’t happen,” Afromowitz commented on potential opponents. “Misaki’s a fighter that we recently signed, so Cung may wind up fighting him or he may just go back and fight Frank (Shamrock) again for his next fight, but he’ll be back.”

Misaki will be the first ranked opponent Le has faced in his MMA career but I don't think he really represents any step up in competition from Frank Shamrock. Misaki will have a considerable size advantage over Le and his unusual striking style gives him a punchers chance against any middleweight.